Histones, Nucleosomes & Kits
The genome in eukaryotic cell is composed of DNA, histone and non-histone proteins, which are assembled into a highly compact structure known as chromatin. Chromatin is a highly complex, dynamic, nucleoprotein structure in the cell nucleus, which orchestrates all nuclear process from DNA replication to DNA repair, from transcription to recombination. The basic structural and functional unit of chromatin is called nucleosome. The nucleosome core particle (NCP), contains approximately 147 bp of DNA wrapped around an octamer of the four core histones (H2A, H2B, H3 and H4) in ~1.7 left-handed super helical turns.
For your important epigenetic experiments, EpiGex offers a large range of high quality products including histones, remodeling factors, epigenetic enzymes... and many others that you will discover in our online catalog.