Recombinant human Hp1γ (CBX3)
Catalog # : EPX-003-REP
Source : Human
Expressed in : E. Coli
Quantity : 25µg of
recombinant human Hp1γ at 0.5µg /µl
Hp1γ (CBX3) associates with euchromatin and is largely
constitutive heterochromatin (1). CBX3 recognizes and binds histone H3
tails methylated at 'Lys-9', leading to epigenetic repression (2). It
seems to be involved in transcriptional silencing in
heterochromatin-like complexes. May be associated with microtubules and
mitotic poles during mitosis (2).
Recombinant human N-terminal His tagged Hp1γ was
produced in E.
Coli, purified using FPLC and formulated in a storage buffer containing
20mM Tris-Cl pH 7.6, 1mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5mM PMSF
and 1mM DTT. Protein concentration was determined by spectrometry.
>98% purity by SDS-PAGE.
Each lot has been evaluated by 10% Tris Glycine SDS-PAGE.
of recombinant Hp1γ (Lane 2). Lane 1, protein molecular
For research use only. Products guaranteed stable for 2
years from date of receipt when stored properly.
>98% purity by SDS PAGE.
(Mw: 21,990 Da.)
1. Minc et al., Chromosoma
2. Lachner et al., Nature